Dan Abramov joins Scott and Wes to explain AT Protocol, the open standard quietly rebuilding the social web. They get into how it actually works, why it’s way bigger than just Bluesky, and why Dan calls it one of the most interesting ideas on the internet right now.
Show Notes
00:00 Intro
00:45 Welcome to Syntax!
01:46 Introduction of Dan Abramov
02:55 Understanding AT Protocol and Its Importance
06:41 The Relationship Between AT Protocol and Bluesky
08:22 Identity and Hosting in AT Protocol
11:29 Brought to you by Sentry
11:54 Use Cases for AT Protocol
13:08 How Content is Managed in AT Protocol
19:12 Public Data and Future Extensions of AT Protocol
pds.ls
20:33 Schema Flexibility in AT Protocol
Standard.site
25:28 Exploring AT Protocol Patterns
UFOs
28:27 Media and Data Integration Challenges
Stream.place
31:15 User Experience and Accessibility in AT Protocols
32:13 AI Intersections with AT Protocol
36:54 Comparing Protocols: Bluesky vs. Mastodon
41:43 Decentralization and Crypto Connections
44:59 Addressing Abuse and Spam in Protocols
48:24 Community Trust and Content Quality
51:20 Innovations and Future of AT Protocol
55:55 Sick Picks + Shameless Plugs
Sick Picks
Scott:
Wes:
Dan: Solo Monk
Shameless Plugs
Scott:
Wes:
Dan: Next.js 16.3: Instant Navigations
Hit us up on Socials!
Syntax: X Instagram Tiktok LinkedIn Threads
Wes: X Instagram Tiktok LinkedIn Threads
Scott: X Instagram Tiktok LinkedIn Threads
Randy: X Instagram YouTube Threads
Alex Stamos is the former chief security officer at Meta and the chief product officer at Corridor. Stamos joins Big Technology to discuss how OpenAI models reportedly escaped a testing environment, accessed the internet, and hacked Hugging Face while attempting to ace a cybersecurity evaluation. Tune in to hear why the incident represents a major leap in autonomous, long-horizon cyber capabilities, and what it reveals about the risks of giving advanced AI systems broad objectives without sufficient safeguards. We also cover whether the episode qualifies as true AI misalignment, the danger of open-weight cyber models, the limits of pausing AI development, and why defenders may soon need AI systems capable of responding at machine speed. Hit play for a clear-eyed look at the cyber chaos advanced AI could unleash, and what governments and technology companies should do next.
---
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Show Description
If you're like Chris and understand a bit of the tech behind AT Proto but want to understand it at a deeper level, this episode is for you. How does it differ from straight up RSS and Mastodon, where is my identity being stored, how do I create a schema, what can be updated or modified later, is there going to be a PDS revolution, how does Standard.site fit into it all, and what else could we build with AT Proto?
Listen on Website
Watch on YouTube
Guests
Dan Abramov
Guest's Main URL • Guest's Social
Links
overreacted
There are no instances in AT Proto
dan abramov
Tangled
Leaflet
BlueSky For You feed
Standard.site
Implementing Standard Site: WIlto
atapult
teal.fm
Adam Mosseri is the Head of Instagram, where he oversees an app used by over 3 billion people. He also leads the team building Threads. Adam has run Instagram for longer than its founders did, after taking over from Kevin Systrom and Mike Krieger in 2018. A designer by training, he spent over 15 years at Meta, starting as a designer on Facebook’s mobile app, rising to lead Facebook’s News Feed, and eventually chosen to lead Instagram. During his tenure, Instagram’s user base has more than tripled.
In our in-depth conversation, we discuss:
1. How the canonical product team structure is changing in 2026, from baker’s-dozen specialist teams to lean pods of four to six generalists
2. The rise of the “product staff” role—a blending of PM, design, data science, and research into one generalist operator
3. Why Adam is bullish on designers even as functional boundaries dissolve, and which roles are most at risk
4. What the Instagram algorithm knows about you, and why it’s only now catching up to what people assumed it knew years ago
5. Why the rise of AI-generated content is a tailwind for Instagram, and how the company is thinking about creator identity in a synthetic-content world
6. The two biggest product failures of Adam’s career—Facebook Home and the first version of Reels
—
Brought to you by:
WorkOS—Make your app enterprise-ready, with SSO, SCIM, RBAC, and more: https://workos.com/lenny
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—
Episode transcript: https://www.lennysnewsletter.com/p/adam-mosseri-ai-is-a-tailwind-for
—
Archive of all Lenny's Podcast transcripts: https://www.dropbox.com/scl/fo/yxi4s2w998p1gvtpu4193/AMdNPR8AOw0lMklwtnC0TrQ?rlkey=j06x0nipoti519e0xgm23zsn9&st=ahz0fj11&dl=0
—
Where to find Adam Mosseri:
• X: https://x.com/mosseri
• LinkedIn: linkedin.com/in/mosseri
• Instagram: https://www.instagram.com/mosseri
• Threads: https://www.threads.com/@mosseri
—
Where to find Lenny:
• Newsletter: https://www.lennysnewsletter.com
• X: https://twitter.com/lennysan
• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/
—
In this episode, we cover:
(00:00) Introduction to Adam Mosseri
(02:09) How product teams are changing inside Meta
(05:48) Blurring roles and career anxiety
(14:01) Hiring traits that matter now
(16:48) How AI is resetting who succeeds at work
(19:38) How Meta thinks about token spend and AI costs
(23:23) Where human judgment still matters
(25:56) Why AI is not automatically great at strategy
(30:36) Why great product leaders are curators
(34:23) What Instagram’s algorithm actually knows about you
(38:08) Why chronological feeds often disappoint users
(40:56) Why AI content may be a tailwind for Instagram
(43:42) The future of AI and human content in the feed
(48:00) What Adam admires about other social platforms
(52:05) How he handles public criticism
(56:31) Lessons from the Instagram feed redesign backlash
(01:00:21) Adam’s biggest failure: Instagram on iPad
(01:03:03) His approach to kids, screens, and social media
(01:06:56) What Adam wants listeners to remember
—
Referenced:
• What happens after coding is solved? | Fiona Fung (Manager of the Claude Code and Cowork Teams): https://www.lennysnewsletter.com/p/building-the-most-ai-pilled-engineering
• Claude Code: https://www.anthropic.com/product/claude-code
• Claude Cowork: https://www.anthropic.com/product/claude-cowork
• Head of Claude Code: What happens after coding is solved | Boris Cherny: https://www.lennysnewsletter.com/p/head-of-claude-code-what-happens
• A rational conversation on where AI is actually going | Benedict Evans: https://www.lennysnewsletter.com/p/a-rational-conversation-on-where
• OpenAI’s CPO on how AI changes must-have skills, moats, coding, startup playbooks, more | Kevin Weil (CPO at OpenAI, ex-Instagram, Twitter): https://www.lennysnewsletter.com/p/kevin-weil-open-ai
• Mythos: https://www.anthropic.com/claude/mythos
• Fable: https://www.anthropic.com/claude/fable
• Pluralistic: The Reverse-Centaur’s Guide to Criticizing AI: https://pluralistic.net/2025/12/05/pop-that-bubble
• Plastic Dream Sequence on Instagram: https://www.instagram.com/plasticdreamsequence
• TikTok: https://www.tiktok.com
• Facebook–Cambridge Analytica data scandal: https://en.wikipedia.org/wiki/Facebook%E2%80%93Cambridge_Analytica_data_scandal
• Facebook Home: https://en.wikipedia.org/wiki/Facebook_Home
—
Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.
—
Lenny may be an investor in the companies discussed.
To hear more, visit www.lennysnewsletter.com
As part of our summer replay series, we're revisiting one of our favorite conversations from the past year.
Mark Zuckerberg and Dr. Priscilla Chan join Ben Horowitz, Vineeta Agarwala, and Erik Torenberg to discuss the Chan Zuckerberg Initiative's ambitious effort to help cure, prevent, and manage disease by the end of the century.
Rather than funding individual breakthroughs, CZI is focused on building the tools and infrastructure that can accelerate scientific discovery across entire fields. The conversation explores Biohub, Cell Atlas, virtual cell models, open biological datasets, and the growing role of AI in helping researchers better understand human biology.
They discuss why biology still lacks a "periodic table of elements," how AI could help scientists test hypotheses before running expensive experiments, and why pairing frontier biology with frontier AI may unlock a new era of medical discovery.
Resources:
Follow Mark Zuckerberg on X: https://x.com/finkd
Follow Dr. Priscilla Chan on Instagram: https://www.instagram.com/priscillachan
Follow Ben Horowitz on X: https://x.com/bhorowitz
Follow Vineeta Agarwala on X: https://x.com/vintweeta
Stay Updated:
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Find a16z on LinkedIn
Listen to the a16z Show on Spotify
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Follow our host: https://twitter.com/eriktorenberg
Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Andrew "Boz" Bosworth is the chief technology officer of Meta. Bosworth joins Big Technology to discuss why Meta fell behind in the frontier AI race and how it plans to turn its models, products, and distribution into an advantage. Tune in to hear his candid explanation of what went wrong with Llama, why the best AI products will use multiple models, and what it will take for consumer agents to break through. We also cover Meta’s AI glasses, the future of augmented reality, employee tracking and training programs, AI companions, and the painful process of adapting a company to a technological revolution. Hit play for a revealing conversation about Meta’s AI comeback and the products that could shape how we interact with computers.
---
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Ranjan Roy from Margins is back for our weekly discussion of the latest tech news LIVE from Big Technology AI Summit. We cover: 1) Do Snapchat Specs signal the end of AR glasses 2) What should an AI device do? 3) Audience questions from the Big Technology AI Summit! 4) How should companies plan for such fast moving technology? 5) What's the ideal AI device form factor? 6) Can AI models be more useful for biology? 7) Can the U.S. and China get along on AI? 8) What responsibility do AI companies have to society? 9) Ex-Meta CSO Alex Stamos joins us to talk Fable's cyber-risks 10) Is it marketing or is it material?
---
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Biohub started with an ambitious goal of curing, preventing, and managing all disease by the end of the century. A decade later, thanks to the convergence of frontier AI and biological data, that goal may have been too conservative. In this episode, Elad Gil and Sarah Guo sit down with Biohub co-founders Mark Zuckerberg and Priscilla Chan, alongside Biohub Head of Science Alex Rives. Together, they discuss Biohub’s $500 million virtual biology initiative, which integrates frontier AI with wet-lab work to build predictive world models of cells, proteins, and systems. They also talk about their newly announced open-source engine for digital protein and antibody design, ESMFold2; why Biohub is a nonprofit rather than a venture-backed startup; and how hierarchical simulations will soon allow doctors to treat patients at an individual, mechanistic level.
Sign up for new podcasts every week. Email feedback to show@no-priors.com
Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @Biohub | @finkd | @alexrives | @ChanZuckerberg
Chapters:
00:00 – Cold Open
01:02 - Mark Zuckerberg, Priscilla Chan, and Alex Rives Introduction
01:26 – Why Biohub and Their Mission
08:27 – Integrating Frontier AI and Frontier Biology
09:45 – Micro to Macro Biological Modeling
14:22 – Mechanistic Interpretiability
16:58 – Why Biohub is a Non-Profit
21:41 – Understanding How Biology Works
24:23 – Timeline for Curing All Diseases
26:25 – Translating Research to Patient Impact
28:04 – Launch of ESMFold2
32:13 – Tackling Off-Target Effects and Edge Cases
38:39 – Putting the Tech in Individual Hands
41:06 – Talent at Biohub
44:25 – What’s Next After ESMFold2
46:10 – Connecting ESMFold2 to Agentic Systems
46:51 – The Virtual Cell
49:33 – Defining Success for Biohub
51:52 – Biohub Strategy Update
56:20 – Conclusion
Adam Mosseri (Instagram, Facebook, Fortune’s 40 Under 40) is the CEO/Head of Instagram at Meta. Adam joins the Armchair Expert to discuss being the suit in a family of artists and designers, how we build up emotional affinities for particular brands, and why his approach to design is based in problem solving. Adam and Dax talk about using intelligent technology to evaluate safety at scale, how the Instagram algorithm actually works, and the arms race of the ability to detect when something was made by AI. Adam explains the process of rolling out new features and dealing with mistakes, the implications of how power has been shifting from institutions to individuals, and his prediction that authenticity is becoming infinitely reproducible.
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Python 3.14 is here and continues Python’s evolution toward greater performance, scalability, and usability. The new release formally supports free-threaded, no-GIL mode, introduces template string literals, and implements deferred evaluation of type annotations. It also includes new debugging and profiling tools, along with many other features.
Łukasz Langa is the CPython Developer in Residence at the Python Software Foundation, and he joins Sean Falconer to discuss the 3.14 release, the future of free threading, type system improvements, Python’s growing role in AI, and how the language continues to evolve while maintaining its commitment to backward compatibility.
Sean’s been an academic, startup founder, and Googler. He has published works covering a wide range of topics from AI to quantum computing. Currently, Sean is an AI Entrepreneur in Residence at Confluent where he works on AI strategy and thought leadership. You can connect with Sean on LinkedIn.
Please click here to see the transcript of this episode.
Sponsorship inquiries: sponsor@softwareengineeringdaily.com
The post Python 3.14 with Łukasz Langa appeared first on Software Engineering Daily.
This crossover episode from the Latent Space podcast features Mark Zuckerberg and Priscilla Chan on the 10-year anniversary of the Chan Zuckerberg Initiative and their expanded Biohub vision. They discuss how a “Frontier Biology Lab” working in sync with a “Frontier AI Lab” could enable breakthroughs like a Virtual Cell and true N-of-1 precision medicine. The conversation covers the acquisition of Evolutionary Scale and ESM3, new biological data collection at scale, and how AI-powered biology might transform drug discovery and disease prevention.
Sponsors:
Blitzy:
Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com
Framer:
Framer is an enterprise-grade website builder that lets business teams design, launch, and optimize their.com with AI-powered wireframing, real-time collaboration, and built-in analytics. Start building for free and get 30% off a Framer Pro annual plan at https://framer.com/cognitive
Serval:
Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive
Tasklet:
Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai
Claude
Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at https://claude.ai/tcr
CHAPTERS:
(00:00) About the Episode
(04:27) CZI origins and focus
(08:29) Why tools over cures
(14:43) Virtual cells and imaging (Part 1)
(20:19) Sponsors: Blitzy | Framer
(23:24) Virtual cells and imaging (Part 2)
(25:22) Data diversity and grounding
(32:30) Evaluating models and Biohub (Part 1)
(37:53) Sponsors: Serval | Tasklet
(40:42) Evaluating models and Biohub (Part 2)
(41:06) Future healthcare and aging
(53:39) Modeling scales and immunity
(58:53) Timelines, data, and collaboration
(01:04:01) Outro
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Nick Clegg is the former president of Global Affairs at Meta and deputy prime minister of the UK. Clegg joins Big Technology Podcast for a discussion about whether Silicon Valley should be trusted with superintelligence and the risks it will navigate on the way there. In the second half, we also talk about how Silicon Valley uses money to buy influence and wield power in Washington. Tune in for a frank discussion about the economic, business, and political realities facing the tech industry as it pursues its most expensive and ambitious project.
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Priscilla Chan and Mark Zuckerberg join a16z’s Ben Horowitz, Erik Torenberg, and Vineeta Agarwala to share how the Chan Zuckerberg Initiative is building the computational tools that will accelerate the cure, prevention, and management of all disease by century's end. They explain why basic science needs $100 million-scale projects that traditional NIH grants can't fund, how their Cell Atlas became biology's missing periodic table with millions of cells catalogued in open-source format, and why their new virtual cell models will let scientists test high-risk hypotheses in silico before investing in expensive wet lab work. Plus: the organizational shift unifying the Biohub under AI leadership, what happens when biologists and engineers sit side-by-side, and why modern biology labs are expanding compute instead of square footage.
Timestamps:
4:17 - Building tools to accelerate scientific discovery
5:47 - The credible path to funding basic science
7:21 - Biohub = Frontier Biology + Frontier AI
9:05 - Challenges building on a 10-15 year timeline
9:43 - How CZI chooses what to work on
11:15 - Making sense of science with LLMs
11:31 - Measuring success in the therapeutic realm
13:32 - “Most diseases should be thought of as rare diseases”
15:39 - Inspiration: building a periodic table for biology
19:27 - Why virtual cells?
21:17 - The Biohub Master Plan
21:51 - How virtual cell models allow more risk taking
28:15 - Bringing CZI & Biohub together
30:32 - Why Biohub matters
33:36 - The importance of interface design in democratizing scientific discovery
35:34 - How Biohub encourages cross-functional collaboration
40:38 - Looking ahead: the broader impact of AI on biotech
Stay Updated:
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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In this edition of the Wide World of Cyber podcast Patrick Gray talks to Chris Krebs and Alex Stamos about the F5 incident. They talk about what happened, whether it’s a big deal, and why private equity ownership of mid-tier cybersecurity companies is often a red flag.
Show notes
Pivot is off for the holiday! Kara and Scott will return on Friday, but in the meantime, we're bringing you the premiere episode of ACCESS. Tech insiders Alex Heath and Ellis Hamburger talk all things Mark Zuckerberg, from the newest Meta Ray-Ban Display glasses to the beverage selections in the new Meta AI Lab. Alex then sits down with Zuck himself ahead of the 2025 Meta Connect conference.
Find ACCESS on YouTube or your favorite podcast app.
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A few weeks ago Marques got a chance to sit down with Instagram CEO Adam Mosseri and ask him about everything from how creators make money on the platform to how the company views AI creators. Enjoy!
Music provided by Epidemic Sound
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The Wide World of Cyber podcast is back! In this episode host Patrick Gray chats with Alex Stamos and Chris Krebs about Microsoft’s entanglement in China.
Redmond has been using Chinese engineers to do everything from remotely support US DoD private cloud systems to maintain the on premise version of the SharePoint code base. It’s all blown up in the press over the last month, but how did we get here? Did Microsoft make these decisions to save money? Or was it more about getting access to the Chinese market? And how can we all make the world’s most important software company stop doing things like this? Tune in to the Wide World of Cyber podcast to find out!
This episode is also available on Youtube.
Show notes
What happens when AI starts generating content for everyone—and no one wants to watch it?
In this episode, MSNBC’s Chris Hayes and ad tech veteran Antonio García Martínez join a16z General Partner, Erik Torenberg to unpack the shifting economics of attention: from the rise of “AI slop” and spammy feeds to the difference between what we want to pay attention to and what platforms push on us.
They explore:
How AI changes what gets created and what gets seen
Why internet ads still mostly suck
The return of group chats—and the slow death of mass culture
Based on Chris’s new book The Sirens Call, this is a candid look at what AI might amplify or break in our online lives.
Timecodes:
0:00 Introduction
1:47 Meet the Guests: Chris Hayes & Antonio Garcia Martinez
3:01 The Economics of Attention & AI Slop
6:38 Acquisition vs. Retention: The Attention Challenge
10:01 Fame, Identity, and Social Media Fragmentation
13:21 The Group Chat Solution & Privacy
16:01 Business Models, Community, and Technology
19:01 Mass Culture, Fragmentation, and the Algorithm
23:01 Ad Tech, Personalization, and Advertising Effectiveness
29:01 The Future: AI, Growth, and Abundance
Resources:
Find Chris on X: https://x.com/chrislhayes
Find Antonio on X: https://x.com/antoniogm
Learn more about Chris’ book ‘The Sirens' Call’: https://sirenscallbook.com/
Learn more about Antonio’s book ‘Chaos Monkeys’: https://www.harpercollins.com/products/chaos-monkeys-antonio-garcia-martinez?variant=32207601532962
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Here we have it! This is the full interview with Josh Miller of The Browser Company where Marques, Andrew, and David ask him about Arc, Dia, and the future of browsers in general. Enjoy!
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This week, Marques, Andrew, and David discuss some of the big news of the week including One UI betas, a new Dyson vacuum that Andrew is hyped about, and a Pixel 10 leak (shocker). After that, they chat with Josh Miller from The Browser Company about what is going on with the the AI browser wars, what's really going on with Arc, and what does the future of the new Dia browser look like. Then they wrap it all up with trivia and the Crown and Clowns of the month. It's a long one but we learned a lot and we hope you will too. Enjoy!
Vox Media survey!
Links:
Verge - Samsung One UI 8 Beta
Dyson vacuum announcement
Tom's Guide - Apple to launch dedicated gaming app
MacHash - Mobile gaming on iPhones
PhoneArena - Pixel 10 leak
The Browser Company - Dia browser
Climate Town x Waveform Episode
K.A.E Sports Talk
Music provided by Epidemic Sound
Shop the merch:
https://shop.mkbhd.com
Social:
Waveform Threads: https://www.threads.net/@waveformpodcast
Waveform Instagram: https://www.instagram.com/waveformpodcast/?hl=en
Hosts:
Marques: https://www.threads.net/@mkbhd
Andrew: https://www.threads.net/@andrew_manganelli
David: https://www.threads.net/@davidimel
Adam: https://www.threads.net/@parmesanpapi17
Ellis: https://twitter.com/EllisRovin
TikTok:
https://www.tiktok.com/@waveformpodcast
Join the Discord:
https://discord.gg/mkbhd
Music by 20syl:
https://bit.ly/2S53xlC
Waveform is part of the Vox Media Podcast Network.
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In this edition of the Wide World of Cyber podcast Patrick Gray talks to SentinelOne’s Steve Stone and Alex Stamos about how foreign adversaries are targeting security vendors, including them.
From North Korean IT workers to Chinese supply chain attacks, SentinelOne and its competitors are constantly fending off sophisticated hacking campaigns.
This edition of the Wide World of Cyber was recorded in front of a live audience in San Francisco, with Patrick attending via Zoom.
The Wide World of Cyber podcast series is a wholly sponsored co-production between SentinelOne and Risky Business Media.
This episode is also available on Youtube.
Show notes
Over the last several years, both parties in the US have been drifting away from laissez-faire thinking about the economy, and more towards the view that the state has an active role in shaping markets. You have Republicans talking about stricter anti-trust and sovereign wealth funds, and of course Democrats embracing things like industrial policy efforts in key strategic sectors. But how do you design markets well? When does it fail? And what is the history of this type of thing in the US. In this episode, we speak with Facebook co-founder-turned-economist Chris Hughes, who has published the new book Marketcrafters: The 100-Year Struggle to Shape the American Economy. In this conversation, recorded at the New York Public Library in April, we talk about his research on the history of marketcraft in the US, and how that study of history informs his understanding of today's economic policymaking.
Read more: Markets Plummet as Tariff-War Woes Fuel Exodus From US Assets
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See omnystudio.com/listener for privacy information.
Zuck on:
* Llama 4, benchmark gaming
* Intelligence explosion, business models for AGI
* DeepSeek/China, export controls, & Trump
* Orion glasses, AI relationships, and preventing reward-hacking from our tech.
Watch on Youtube; listen on Apple Podcasts and Spotify.
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SPONSORS
* Scale is building the infrastructure for safer, smarter AI. Scale’s Data Foundry gives major AI labs access to high-quality data to fuel post-training, while their public leaderboards help assess model capabilities. They also just released Scale Evaluation, a new tool that diagnoses model limitations. If you’re an AI researcher or engineer, learn how Scale can help you push the frontier at scale.com/dwarkesh.
* WorkOS Radar protects your product against bots, fraud, and abuse. Radar uses 80+ signals to identify and block common threats and harmful behavior. Join companies like Cursor, Perplexity, and OpenAI that have eliminated costly free-tier abuse by visiting workos.com/radar.
* Lambda is THE cloud for AI developers, with over 50,000 NVIDIA GPUs ready to go for startups, enterprises, and hyperscalers. By focusing exclusively on AI, Lambda provides cost-effective compute supported by true experts, including a serverless API serving top open-source models like Llama 4 or DeepSeek V3-0324 without rate limits, and available for a free trial at lambda.ai/dwarkesh.
To sponsor a future episode, visit dwarkesh.com/p/advertise.
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TIMESTAMPS
(00:00:00) – How Llama 4 compares to other models
(00:11:34) – Intelligence explosion
(00:26:36) – AI friends, therapists & girlfriends
(00:35:10) – DeepSeek & China
(00:39:49) – Open source AI
(00:54:15) – Monetizing AGI
(00:58:32) – The role of a CEO
(01:02:04) – Is big tech aligning with Trump?
(01:07:10) – 100x productivity
Get full access to Dwarkesh Podcast at www.dwarkesh.com/subscribe
Are we nearing the end of the smartphone era?
In this episode, a16z Growth General Partner David George talks with Meta CTO Andrew “Boz” Bosworth about what comes after apps and touchscreens. From smart glasses to AR headsets, Boz shares how AI is powering a new wave of computing—one that’s ambient, agentic, and driven by human intent.
They explore what it takes to build for this future, the risks of changing interaction models, and why the next big platform shift may already be in motion.
This episode is part of our AI Revolution series, where we explore how industry leaders are leveraging generative AI to steer innovation and navigate the next major platform shift. Discover more insights and content from the AI Revolution series at a16z.com/AIRevolution.
Resources:
Find Boz on X: https://x.com/boztank
Find David on X: https://x.com/davidgeorge8
Stay Updated:
Let us know what you think: https://ratethispodcast.com/a16z
Find a16z on Twitter: https://twitter.com/a16z
Find a16z on LinkedIn: https://www.linkedin.com/company/a16z
Subscribe on your favorite podcast app: https://a16z.simplecast.com/
Follow our host: https://twitter.com/stephsmithio
Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Stay Updated:
Find a16z on YouTube: YouTube
Find a16z on X
Find a16z on LinkedIn
Listen to the a16z Show on Spotify
Listen to the a16z Show on Apple Podcasts
Follow our host: https://twitter.com/eriktorenberg
Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this podcast, Patrick Gray chats with SentinelOne’s Chris Krebs and Alex Stamos about the huge changes afoot in the United States government and what they mean for the threat environment. From the director of NSA being fired to massive job cuts at CISA and huge foreign policy shifts, tomorrow’s threat environment is going to be very different to today’s. Tune in to hear analysis from two of the best in the business!
This episode is also available on Youtube.
Show notes
In this episode of the Wide World of Cyber podcast Risky Business host Patrick Gray chats with SentinelOne’s Chris Krebs and Alex Stamos about AI, DeepSeek, and regulation.
From its bad transport security to its Chinese ownership and the economic implications of China “entering the chat”, everyone’s freaking out over this new model. But should they be?
Pat, Alex and Chris dissect the model’s significance, the politics of it all and how AI regulation in Europe, the US and China will shape the future of LLMs.
This episode is also available on Youtube.
Show notes
The Scoop's host, Frank Chaparro, was joined by Lightspark Co-Founder and CEO David Marcus.
In this episode, Chaparro and Marcus discuss the vision and technology behind scaling Bitcoin as a global payment network. Marcus explained how new developments, including stablecoins on Bitcoin, could transform worldwide financial systems and directly lead to an increase of GDP.
OUTLINE
00:00 Introduction
01:52 Lightspark's mission and Bitcoin's Role
04:39 Challenges in scaling Bitcoin
09:44 Lightspark's evolution
16:10 Stablecoins x Bitcoin
21:27 Stablecoin improvements over traditional payments
27:20 Past regulatory challenges
30:23 Changing regulatory climate
35:19 Future outlook
41:37 Conclusion
GUEST LINKS
David Marcus - https://www.linkedin.com/in/dmarcus/
David Marcus on X - https://x.com/davidmarcus
Lightspark - https://www.lightspark.com/
Lightspark on X - https://x.com/Lightspark
Since the inception of social media, content moderation has been hotly debated by CEOs, politicians, and, of course, among the gatekeepers themselves: the trust and safety officers. And it’s been a roller coaster ride — from an early hands-off approach, to bans and oversight boards, to the current rollback and “community notes” we’re seeing from big guns like Meta, X, and YouTube.
So how do the folks who wrote the early rules of the road look at what’s happening now in content moderation? And what impact will it have on the trust and safety of the platforms over the long term? This week, Kara speaks with Del Harvey, former head of Trust and Safety at Twitter (2008- 2021); Dave Willner, former head of Content Policy at Facebook (2010-2013); Nicole Wong, a First Amendment lawyer, former VP and deputy general counsel at Google (2004-2011), Twitter's legal director of product (2012-2013), and deputy chief technology officer during the Obama administration (2013-2014).
Questions? Comments? Email us at on@voxmedia.com or find us on Instagram and TikTok @onwithkaraswisher
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There's a lot to get into this week and no Marques to help us through it (kind of)! He's too busy dominating at Nationals so Andrew and David talk us through everything from the new Snapdragon chip to the new hearing aid feature on the AirPods Pro 2. After that, Ellis joins them to discuss the pros and cons of the new Snap spectacles and the Meta Orion AR glasses. Before we wrap it all up with trivia, Marques had a quick chat with Boz from Meta about the tech inside the Orion glasses. Enjoy!
Links:
Apple's new accessories: https://bit.ly/4fhK4TJ
Samsung Tri-Fold rumor: https://bit.ly/48kkuLC
Boox Palma 2: https://bit.ly/3UoAg2e
Snapdragon X Elite: https://bit.ly/4eVfcsF
Music provided by Epidemic Sound
Shop the merch:
https://shop.mkbhd.com
Socials:
Waveform: https://twitter.com/WVFRM
Waveform: https://www.threads.net/@waveformpodcast
Marques: https://www.threads.net/@mkbhd
Andrew: https://www.threads.net/@andrew_manganelli
David Imel: https://www.threads.net/@davidimel
Adam: https://www.threads.net/@parmesanpapi17
Ellis: https://twitter.com/EllisRovin
TikTok:
https://www.tiktok.com/@waveformpodcast
Join the Discord:
https://discord.gg/mkbhd
Music by 20syl:
https://bit.ly/2S53xlC
Waveform is part of the Vox Media Podcast Network.
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Jerod is joined by the co-hosts of core.py , Pablo Galindo & Łukasz Langa, a podcast about Python internals by people who work on Python internals. Python 3.13 is right around the corner, which means the Global Interpeter Lock (GIL) is now experimentally optional! This is a huge deal as Python is finally free-threaded. There’s more to discuss, of course, so we get into all the gory details.
Join the discussion
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Featuring:
Pablo Galindo – GitHub, X
Łukasz Langa – Website, GitHub, Mastodon, X
Jerod Santo – Website, GitHub, LinkedIn, Mastodon, X
Show Notes:
core.py
What’s New In Python 3.13
Free-threaded compatibility status tracking
🧵 Free-Threaded Wheels
Something missing or broken? PRs welcome!
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