Author Jim Collins on unlocking your potential
Jim Collins is the author of some of the most important business books of all time, like Good to Great and Built to Last. For his latest project, instead of profiling iconic companies, he zoomed in on extraordinary individuals we can learn from. He joined host Jeff Berman to reveal how icons like Grace Hopper and John Glenn illustrate lessons on how to navigate the cliffs and fog of life.
Find out more about the book: jimcollins.com
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AI Discovered Antibiotics: How Small Data & Small GNNs Led to Big Results, w/ MIT Prof. Jim Collins
Jim Collins, Termeer Professor at MIT, unveils his AI-powered project that has discovered several new antibiotics, effective against resistant strains and often employing entirely new mechanisms of action. He details how their refined multi-step AI process, even with small datasets and modest compute, can efficiently screen vast chemical spaces to identify promising drug candidates. This breakthrough offers a realistic and affordable path to tackling the staggering antibiotic resistance crisis, which currently claims over a million lives annually. Collins argues this practical application of AI represents a transformative win for humanity, often overlooked amidst the focus on AGI.
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CHAPTERS:
(00:00) About the Episode
(04:30) Introducing Jim Collins
(05:26) Antibiotic Resistance Primer
(14:04) The Antibiotic Market Failure
(18:45) AI Discovers Halicin (Part 1)
(18:51) Sponsors: AssemblyAI Ad 1 | Claude
(22:11) AI Discovers Halicin (Part 2)
(30:58) The Economics of Discovery
(39:10) Inside the AI Architecture (Part 1)
(39:17) Sponsors: Linear | AGNTCY | Shopify
(43:47) Inside the AI Architecture (Part 2)
(01:00:13) Human-in-the-Loop Discovery
(01:12:12) Novel Mechanisms & Properties
(01:19:02) Future Applications & Risks
(01:27:01) A Call to Action
(01:28:04) Outro
How we're using AI to discover new antibiotics | Jim Collins
Before the coronavirus pandemic, bioengineer Jim Collins and his team combined the power of AI with synthetic biology in an effort to combat a different looming crisis: antibiotic-resistant superbugs. Collins explains how they pivoted their efforts to begin developing a series of tools and antiviral compounds to help fight COVID-19 -- and shares their plan to discover seven new classes of antibiotics over the next seven years. (This ambitious plan is a part of The Audacious Project, TED's initiative to inspire and fund global change.)
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Recode Decode: “Good to Great” author Jim Collins
Jim Collins, the author of business books such as Built to Last and Good to Great, talks with Recode's Kara Swisher about his latest work, Turning the Flywheel.
In this episode: Collins’ background in business education; his mentor and Stanford colleague Jerry Porras; his past books, including Built to Last and How the Mighty Fall; why he left Stanford and moved to Boulder, Colorado; teaching Jeff Bezos and Amazon how to save the company; how to be a “level-five” leader; what Bill Hewlett and David Packard understood about corporate responsibility; who today is a level-five leader?; the difference between your practices and the core of your beliefs; does tech even have a core?; why the innovators don’t always win; how important is luck?; how is the 2019 bubble different from 1999?; and how Jack Bogle and Steve Jobs stayed young until they died.
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