#373 – Manolis Kellis: Evolution of Human Civilization and Superintelligent AI
Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors:
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EPISODE LINKS:
Manolis Website: http://web.mit.edu/manoli/
Manolis Twitter: https://twitter.com/manoliskellis
Manolis YouTube: https://youtube.com/@ManolisKellis1
PODCAST INFO:
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Spotify: https://spoti.fi/2nEwCF8
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SUPPORT & CONNECT:
– Check out the sponsors above, it’s the best way to support this podcast
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OUTLINE:
Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.
(00:00) – Introduction
(06:44) – Humans vs AI
(15:50) – Evolution
(37:34) – Nature vs Nurture
(50:03) – AI alignment
(56:27) – Impact of AI on the job market
(1:08:06) – Human gatherings
(1:13:07) – Human-AI relationships
(1:23:11) – Being replaced by AI
(1:35:37) – Fear of death
(1:47:33) – Consciousness
(1:54:58) – AI rights and regulations
(2:00:41) – Halting AI development
(2:13:52) – Education
(2:19:16) – Biology research
(2:26:36) – Meaning of life
(2:29:09) – Loneliness
#142 – Manolis Kellis: Meaning of Life, the Universe, and Everything
Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors:
– Grammarly: https://grammarly.com/lex to get 20% off premium
– Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil
– Cash App: https://cash.app/ and use code LexPodcast to get $10
EPISODE LINKS:
Manolis Website: http://web.mit.edu/manoli/
Manolis Twitter: https://twitter.com/manoliskellis
Manolis YouTube: https://www.youtube.com/channel/UCkKlJ5LHrE3C7fgbnPA5DGA
PODCAST INFO:
Podcast website: https://lexfridman.com/podcast
Apple Podcasts: https://apple.co/2lwqZIr
Spotify: https://spoti.fi/2nEwCF8
RSS: https://lexfridman.com/feed/podcast/
YouTube Full Episodes: https://youtube.com/lexfridman
YouTube Clips: https://youtube.com/lexclips
SUPPORT & CONNECT:
– Check out the sponsors above, it’s the best way to support this podcast
– Support on Patreon: https://www.patreon.com/lexfridman
– Twitter: https://twitter.com/lexfridman
– Instagram: https://www.instagram.com/lexfridman
– LinkedIn: https://www.linkedin.com/in/lexfridman
– Facebook: https://www.facebook.com/LexFridmanPage
– Medium: https://medium.com/@lexfridman
OUTLINE:
Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.
(00:00) – Introduction
(06:48) – Music and life
(46:21) – The number 42
(52:22) – The question about the meaning of life
(55:02) – Are humans unique in the universe?
(1:00:46) – Human civilization
(1:12:52) – Mars
(1:14:45) – Human mind and the abstraction layers of reality
(1:25:38) – Neural networks and intelligence
(1:32:55) – Ideas as organisms
(1:42:19) – Language
(1:53:34) – Legacy
(2:08:25) – Poems
SONGS MENTIONED:
[1] Dwros Gewrgiadis – An imoun plousios
https://www.youtube.com/watch?v=7akZoEQv6jI
[2] Grigoris Bithikotsis – Ftoxologia
https://www.youtube.com/watch?v=TyGR24O0KQ8
[3] Sto perigiali to kryfo
https://www.youtube.com/watch?v=B-GBPx_GXQw
[4] Michael Jackson – Man in the Mirror
https://www.youtube.com/watch?v=Zqe5NP86OCc
[5] George Michael – Careless Whisper
https://www.youtube.com/watch?v=izGwDsrQ1eQ
[6] Gainsbourg with Isabelle Adjani – Pull Marine
https://www.youtube.com/watch?v=o7MwHGHWgLk
[7] Georges Moustaki – Le meteque
https://www.youtube.com/watch?v=MV8fGf-N06A
[8] Jacques Brel – Ne me quitte pas
https://www.youtube.com/watch?v=q_bq5mStroM
[9] Sting – Englishman In New York
https://www.youtube.com/watch?v=d27gTrPPAyk
[10] Sting – Fragile
https://www.youtube.com/watch?v=lB6a-iD6ZOY
[11] Pink Floyd – The Wall (When the Tigers Broke Free)
https://www.youtube.com/watch?v=l9b9UhFe6Eg
[12] Pink Floyd – The Wall (One Of My Turns)
https://www.youtube.com/watch?v=BOay-7aqLks
[13] Sting – Russians
https://www.youtube.com/watch?v=wHylQRVN2Qs
[14] Joni Mitchell – Both sides now
https://www.youtube.com/watch?v=aCnf46boC3I
[15] Leonard Cohen – I’m Your Man
https://www.youtube.com/watch?v=yOnXe8ttmjY
[16] Alison Krauss & Union Station – The Lucky One
https://www.youtube.com/watch?v=jcRZ_J_VgNc
#133 – Manolis Kellis: Biology of Disease
Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors:
– SEMrush: https://www.semrush.com/partner/lex/ to get a free month of Guru
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EPISODE LINKS:
Manolis Website: http://web.mit.edu/manoli/
Manolis Twitter: https://twitter.com/manoliskellis
Manolis YouTube: https://www.youtube.com/channel/UCkKlJ5LHrE3C7fgbnPA5DGA
Manolis Wikipedia: https://en.wikipedia.org/wiki/Manolis_Kellis
PODCAST INFO:
Podcast website: https://lexfridman.com/podcast
Apple Podcasts: https://apple.co/2lwqZIr
Spotify: https://spoti.fi/2nEwCF8
RSS: https://lexfridman.com/feed/podcast/
YouTube Full Episodes: https://youtube.com/lexfridman
YouTube Clips: https://youtube.com/lexclips
SUPPORT & CONNECT:
– Check out the sponsors above, it’s the best way to support this podcast
– Support on Patreon: https://www.patreon.com/lexfridman
– Twitter: https://twitter.com/lexfridman
– Instagram: https://www.instagram.com/lexfridman
– LinkedIn: https://www.linkedin.com/in/lexfridman
– Facebook: https://www.facebook.com/LexFridmanPage
– Medium: https://medium.com/@lexfridman
OUTLINE:
Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.
00:00 – Introduction
08:05 – Molecular basis for human disease
32:04 – Deadliest diseases
37:47 – Genetic component of diseases
46:38 – Genetic understanding of disease
1:02:25 – Unified theory of human disease
1:08:26 – Genome circuitry
1:33:29 – CRISPR
1:45:06 – Mitochondria
1:53:10 – Future of biology research
2:22:46 – The genetic circuitry of disease
#123 – Manolis Kellis: Origin of Life, Humans, Ideas, Suffering, and Happiness
Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group.
Please check out our sponsors to get a discount and to support this podcast:
– Public Goods: https://publicgoods.com/lex and use code LEX
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Lex Fridman Podcast survey mentioned in the intro: https://www.surveygizmo.com/s3/5833660/Lex-Fridman-Podcast-Survey
If you would like to get more information about this podcast go to https://lexfridman.com/podcast or connect with @lexfridman on Twitter, LinkedIn, Facebook, Medium, or YouTube where you can watch the video versions of these conversations. If you enjoy the podcast, please rate it 5 stars on Apple Podcasts, follow on Spotify, or support it on Patreon.
Here’s the outline of the episode. On some podcast players you should be able to click the timestamp to jump to that time.
OUTLINE:
00:00 – Introduction
06:20 – Epigenome
10:28 – Evolution
15:26 – Neanderthals
27:15 – Origin of life on Earth
43:44 – Life is a fight against physics
49:56 – Life as a set of transformations
51:35 – Time scales
1:00:31 – Transformations of ideas in human civilization
1:05:19 – Life is more than a rat race
1:13:18 – Life sucks sometimes and that’s okay
1:30:16 – Getting older
1:36:21 – The best of MIT
1:49:01 – Poem 1: The Snow
2:01:52 – Love
2:06:16 – Poem 2: The Tide Waters
#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics
Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group. He is interested in understanding the human genome from a computational, evolutionary, biological, and other cross-disciplinary perspectives.
Support this podcast by supporting our sponsors:
– Blinkist: https://blinkist.com/lex
– Eight Sleep: https://eightsleep.com/lex
– MasterClass: https://masterclass.com/lex
If you would like to get more information about this podcast go to https://lexfridman.com/ai or connect with @lexfridman on Twitter, LinkedIn, Facebook, Medium, or YouTube where you can watch the video versions of these conversations. If you enjoy the podcast, please rate it 5 stars on Apple Podcasts, follow on Spotify, or support it on Patreon.
Here’s the outline of the episode. On some podcast players you should be able to click the timestamp to jump to that time.
OUTLINE:
00:00 – Introduction
03:54 – Human genome
17:47 – Sources of knowledge
29:15 – Free will
33:26 – Simulation
35:17 – Biological and computing
50:10 – Genome-wide evolutionary signatures
56:54 – Evolution of COVID-19
1:02:59 – Are viruses intelligent?
1:12:08 – Humans vs viruses
1:19:39 – Engineered pandemics
1:23:23 – Immune system
1:33:22 – Placebo effect
1:35:39 – Human genome source code
1:44:40 – Mutation
1:51:46 – Deep learning
1:58:08 – Neuralink
2:07:07 – Language
2:15:19 – Meaning of life
