20VC: Lessons from Jensen Huang on "Founder Mode" | How to Know if OpenAI or Anthropic Will Kill your Company | How USV Liking Music Made Them $1BN on an Investment | The Five Year Desert to Product Market Fit & a $5.3BN Valuation with Shiv Rao @ Abridge
Shiv Rao is the CEO and Co-Founder of Abridge, a leader in generative AI for healthcare. The company reached a $5.3 billion valuation following a $300 million funding round with investors including Jensen Huang, Henry Kravis, USV, Bessemer Venture Partners and Elad Gill. A practicing cardiologist, Shiv has scaled the company to 450 employees and partnered with major health systems like Emory and Yale.
AGENDA:
04:00 — You just have to survive long enough to not die
06:00 — Did USV liking music make them billions of dollars?
13:58 — The three variants of an AI native company
15:00 — How do you know if foundation models are going to kill or help you?
22:15 — Why OpenAI and Anthropic doing consultancies is such an obvious move
41:00 — Biggest lesson from Jensen Huang at Nvidia
41:00 — What Founder Mode truly means
52:00 — What the founder of Duolingo taught me about sacrifice
56:37 — If I started a company again, Elad Gill would be the one investor I go to
The Best of 2025 (So Far) with Sarah Guo and Elad Gil
2025 has thus far been a year of great leaps and advances in AI technology. And Sarah and Elad have spoken with some of the most enterprising founders and scientific minds in the field of AI today. So we’re revisiting a few of our favorite conversations on No Priors so far in 2025 – Winston Weinberg (Harvey), Dr. Fei-Fei Li (World Labs), Brendan Foody (Mercor), Dan Hendrycks (Center for AI Safety), Noubar Afeyan (Flagship Pioneering), Brandon McKinzie and Eric Mitchell (OpenAI o3), Isa Fulford (OpenAI), Arvind Jain (Glen), and Dr. Shiv Rao (Abridge).
Sign up for new podcasts every week. Email feedback to show@no-priors.com
Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil
Chapters:
00:00 – Episode Introduction
0:21 – Winston Weinberg on Leaning into New Capabilities
02:01 – Dr. Fei-Fei Li on Spatial Intelligence
04:13 – Brendan Foody on AI Disruption in the Workforce
06:10 – Dan Hendrycks on the Geopolitics of Superintelligence
08:06 – Noubar Afeyan on Entrepreneurship
10:38 – Brandon McKinzie and Eric Mitchell on Reasoning Models
12:41 – Isa Fulford on Training Deep Research
13:49 – Arvind Jain on Innovating Enterprise Search
16:21 – Dr. Shiv Rao on AI’s Human Impact
18:58 – Conclusion
Conversations Are the Source of Truth in Healthcare with Abridge CEO Shiv Rao
In this episode of No Priors, Elad and Sarah chat with Shiv Rao, MD, founder and CEO of Abridge. They dive into how Abridge is reshaping healthcare by creating AI tools that enhance clinical documentation and improve doctor-patient interactions. Shiv shares his thoughts on building trust with established healthcare systems, giving agency and time back to clinicians, and what makes the healthcare AI opportunity different today. They also discuss Abridge’s approach to developing and launching AI products, along with Shiv’s journey in founding Abridge.
Sign up for new podcasts every week. Email feedback to show@no-priors.com
Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @ShivdevRao
Show Notes:
0:00 Introduction
0:35 Abridge’s Story and Vision
5:30 Strategy for Customer Choice
7:41 Healthcare AI Opportunities
11:24 Navigating Incumbent Partnerships
14:26 Doctor-Centric AI Solutions
19:54 Abridge’s Future Plans
22:13 AI’s Impact on Healthcare
28:43 Shipping and Iterating Products
32:50 Shiv’s Journey to Abridge
Next Unicorns: Building the future of healthcare communication with Abridge CEO Shiv Rao | E1784
This Week in Startups is brought to you by…
Crowdbotics. Great ideas can change the world, and Crowdbotics is the fastest way to turn those ideas into code. Get a free scoping session for your next big app idea at crowdbotics.com/twist
Vanta. Compliance and security shouldn't be a deal-breaker for startups to win new business. Vanta makes it easy for companies to get a SOC 2 report fast. TWiST listeners can get $1,000 off for a limited time at vanta.com/twist
LinkedIn Marketing. To redeem a $100 LinkedIn ad credit and launch your first campaign, go to linkedin.com/thisweekinstartups
*
Today’s show:
Abridge CEO Shiv Rao joins Jason to discuss how his AI platform saves doctors time by automating consultation note-taking(8:29), the future of the medical field(37:23), and much more!
*
Time stamps:
(00:00) Abridge CEO and Co-Founder Dr. Shiv Rao joins Jason
(3:22) Abridge's journey and tailwinds in the industry
(6:43) The sudden advancement in AI tech
(8:29) The importance of conversation in healthcare
(12:00) Crowdbotics - Get a free scoping session for your next big app idea at crowdbotics.com/twist
(13:29) Dr. Shiv demos Abridge
(21:49) Reinforcement training and building trustworthy models
(23:10) Use of this product in the field and feedback from clinics
(26:53) Vanta - Get $1000 off your SOC 2 at https://vanta.com/twist
(28:00) Time saved using Abridge
(30:30) How patients interact with Abridge and data privacy
(35:56) LinkedIn Marketing - Get a $100 LinkedIn ad credit at https://linkedin.com/thisweekinstartups
(37:23) The future of the medical field
(49:11) The pace of healthcare today
*
Check out Abridge: https://www.abridge.com/
Follow Dr. Shiv: https://twitter.com/shivdevrao
*
Read LAUNCH Fund 4 Deal Memo: https://www.launch.co/four
Apply for Funding: https://www.launch.co/apply
Buy ANGEL: https://www.angelthebook.com
Great recent interviews: Steve Huffman, Brian Chesky, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland, PrayingForExits, Jenny Lefcourt
Check out Jason’s suite of newsletters: https://substack.com/@calacanis
*
Follow Jason:
Twitter: https://twitter.com/jason
Instagram: https://www.instagram.com/jason
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
*
Follow TWiST:
Substack: https://twistartups.substack.com
Twitter: https://twitter.com/TWiStartups
YouTube: https://www.youtube.com/thisweekin
*
Subscribe to the Founder University Podcast: https://www.founder.university/podcast
