Topology Ventures

Welcome to The Chopping Block – where crypto insiders Haseeb Qureshi, Tom Schmidt, Tarun Chitra, and Robert Leshner get together and give the industry insider's perspective on crypto. This week, special guest Casey Caruso from Topology joins the crew to tackle the latest in crypto and tech. They explore the rise of AI memecoins like Freysa, blending gamified AI agents with blockchain mechanics, and the fallout from a major hack. The discussion also highlights Hyperliquid’s $1.9 billion airdrop and its no-VC funding model, signaling new trends in token launches. The crew critiques decentralized science (DeSci), questioning its accountability and funding models, with a spotlight on Pump.Science’s tokenized longevity experiments. Finally, they examine the success of Base’s incentive-light approach and the impact of frameworks like Eliza on crypto’s evolution. Tune in for a dynamic take on innovation, trends, and challenges shaping the crypto world. Listen to the episode on Apple Podcasts, Spotify, Overcast, Podcast Addict, Pocket Casts, Pandora, Castbox, Google Podcasts, TuneIn, Amazon Music, or on your favorite podcast platform. Show highlights 🔹 The Rise of AI Memecoins: Exploring the explosive trend of AI memecoins like Freysa, their gamification, and unique mechanics. The crew delves into how these coins combine on-chain activity with AI, creating a new layer of engagement and speculation. 🔹 Freysa’s AI: A detailed look at how Freysa’s prize pool was jailbroken, the mechanics behind the attack, and what it reveals about the vulnerabilities of AI agents connected to smart contracts. 🔹 AI Agents and Crypto Innovation: An overview of AI-enabled agents and their crossover into crypto applications, with insights on current limitations, gamification trends, and how AI integrates with Web3 frameworks like Eliza. 🔹 Airdrop Trends and Hyperliquid: Breaking down Hyperliquid’s $1.9 billion airdrop, its innovative “no VC funding” model, and the market impact of launching into a bull market with a high float percentage. 🔹 The Decentralized Science Debate: Analyzing the potential and pitfalls of decentralized science (DeSci), including critiques of funding mechanisms, accountability, and the practicality of crowdfunding drug discovery through tokenized models. 🔹 Base’s Community-Led Success: Examining how Base has attracted top developers and projects without heavy incentive programs, reshaping the playbook for L1 and L2 ecosystems. 🔹 Pump.Science and Longevity Tokens: A closer look at Pump.Science’s tokenized longevity experiments, the mechanics of its funding model, and the aftermath of its private key leak. 🔹 Challenges of Token-Based Funding: Comparing decentralized incentive models for projects like DeSci with the successes and lessons learned from DeFi, highlighting the difficulty of creating effective accountability mechanisms. 🔹 The DAO Debate: Examining the viability of DAOs for deploying funds in high-stakes environments, with skepticism about their long-term effectiveness in innovation. Hosts ⭐️Haseeb Qureshi, Managing Partner at Dragonfly ⭐️Robert Leshner, CEO & Co-founder of Superstate ⭐️Tarun Chitra, Managing Partner at Robot Ventures Guest: ⭐️Casey Caruso, Founder Topology  Disclosures Timestamps  00:00 Intro 01:24 AI Memecoins & Freysa Challenge 07:07 Open Source Models & Security 21:15 Hyperliquid Airdrop 31:16 Blur vs. Blast Points 37:16 Decentralized Science (DeSci) 40:04 Criticisms of DeSci 48:18 Potential & Future of DeSci Learn more about your ad choices. Visit megaphone.fm/adchoices

Casey Caruso

Founder

TopologyTopology Ventures

In this episode, we explore the critical intersection of AI and crypto with Casey Caruso and Mohamed Baioumy. They delve into why decentralization could be the key to democratizing AI, unpack edge computing, local AI models, and the potential for crypto and AI. We also tackle the challenges of privacy, the importance of solving real-world problems, and the broader implications of AI development on society. Thanks for tuning in! Resources https://www.topology.vc/deai-map - - Start your day with crypto news, analysis and data from Katherine Ross and David Canellis. Subscribe to the Empire newsletter: https://blockworks.co/newsletter/empire?utm_source=podcasts Follow Casey: https://x.com/caseykcaruso Follow Mohamed: https://x.com/mo_baioumy Follow Jason: https://twitter.com/JasonYanowitz Follow Santiago: https://twitter.com/santiagoroel Follow Empire: https://twitter.com/theempirepod Subscribe on YouTube: https://tinyurl.com/4fdhhb2j Subscribe on Apple: https://tinyurl.com/mv4frfv7ww Subscribe on Spotify: https://tinyurl.com/wbaypprw Get top market insights and the latest in crypto news. Subscribe to Blockworks Daily Newsletter: https://blockworks.co/newsletter/ - - The 6th edition of Meridian, a web3 conference hosted by the Stellar Development Foundation is happening in London, England October 15-17, 2024. Learn more and get your early-bird priced tickets now at meridian.stellar.org by using the code BLOCKWORKSPOD. - - Harpie sets the standard in on-chain security, actively monitoring and safeguarding your crypto wallet against theft in real time. It detects, blocks, and recovers stolen assets from risky transactions before they execute, shielding you from even the most advanced hacks and scams. Harpie is free to use and compatible with all Ethereum, Base, Polygon, and Arbitrum wallets. Protect your crypto today at harpie.io. - - Polygon Labs is developing the next generation of open source zero-knowledge tech to aggregate crypto liquidity and user bases with the AggLayer. To support the aggregated future, the Polygon Community Grants Program was launched with 1 billion tokens — all for Polygon builders. Season One of the community grants program is live now, and features 35 million in MATIC to support the next generation of Polygon projects! Join the aggregated future today by applying at https://polygon.technology/grants - - Timestamps: 00:00 Intro 02:00 What's Happening in Crypto AI 10:21 What is Possible with Crypto & AI 16:28 Usecase of Privacy in AI 21:45 Privacy & Local AI Models 32:11 Stellar Ad 33:02 Polygon Ad 34:09 Harpie Ad 35:24 Overrated AI 46:11 Inevitability of AI Agents Using Crypto 01:05:23 Is AI & Crypto Inevitable - - Disclaimer: Nothing said on Empire is a recommendation to buy or sell securities or tokens. This podcast is for informational purposes only, and any views expressed by anyone on the show are solely our opinions, not financial advice. Santiago, Jason, and our guests may hold positions in the companies, funds, or projects discussed.

Casey Caruso

Founder

TopologyTopology Ventures

Mohamed Baioumy

In this episode, host Santi dives into AI and it's intersection with Crypto. Joined by Casey and Daniel, they investigate AI's key innovations, centralizing tendency, and the importance of zero-knowledge proofs in merging AI and crypto. They address the potential challenges and opportunities presented by decentralized networks and GPUs. The chat extends to AI regulation, non-deterministic AI's issues in production, and AI model insurance. Stay tuned for all of this and much more! - - Follow Casey: https://twitter.com/caseykcaruso Follow Daniel: https://twitter.com/realDanielShorr Follow Santiago: https://twitter.com/santiagoroel Follow Empire: https://twitter.com/theempirepod Subscribe on YouTube: https://tinyurl.com/4fdhhb2j Subscribe on Apple: https://tinyurl.com/mv4frfv7 Subscribe on Spotify: https://tinyurl.com/wbaypprw Get top market insights and the latest in crypto news. Subscribe to Blockworks Daily Newsletter: https://blockworks.co/newsletter/ - - Join us at DAS (Digital Asset Summit) in London this March! DAS is the #1 institutional conference in crypto, hosted by Blockworks. Use the link below to learn more, and use EMPIRE20 to get 20% off your ticket! Sign up now because the price goes up every month. See you there! Learn more + get your ticket here: https://blockworks.co/event/digital-asset-summit-2024-london/home - - Timestamps (00:02) Evolution and State of AI (18:03) Model Specialization (30:37) Productization of AI (34:46) Crypto & AI Intersection (49:34) DAS 2024 (50:51) How Real is AI & Crypto (01:00:08) Performant Blockchains vs Ethereum (01:09:32) Decentralized Compute & Equitable GPU Access (01:17:18) First Crypto & AI Unlocks (01:32:18) AI & Crypto Debate - - Disclaimer: Nothing said on Empire is a recommendation to buy or sell securities or tokens. This podcast is for informational purposes only, and any views expressed by anyone on the show are solely our opinions, not financial advice. Santiago, Jason, and our guests may hold positions in the companies, funds, or projects discussed.

Casey Caruso

Founder

TopologyTopology Ventures

Daniel Shorr

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